Exemestane FAQ

What is Exemestane?

Exemestane is an anti-estrogen medication that is medically used in the treatment (or prevention) of hormone receptor-positive breast cancer in postmenopausal women, but it is also very popular in bodybuilding. It is used off-label to lower estrogen levels that can increase due to the use of anabolic steroids. Exemestane (Aromasin – the most popular brand name, among others) is an aromatase inhibitor (AI) because it works by blocking aromatase enzymes. This helps lower estrogen levels in the body. That’s why it helps treat or prevent breast cancer type that forms and grows due to estrogen (by lowering estrogen) and helps in bodybuilding among those who use anabolic steroids that convert into estrogen (via the aromatization process). This leads to high estrogen levels when using those steroids, causing side effects like gynecomastia, water retention, and others. Aromasin helps counteract those side effects while using steroids by reducing estrogen levels.

What are the worst side effects of Exemestane?

The worst side effects of Exemestane (Aromasin) are associated with the fact that it works as an aromatase inhibitor, lowering estrogen levels. If the estrogen levels are too low and/or suppressed for too long, side effects are very likely to occur. Generally, this medication is very well tolerated. However, it can still cause a wide range of side effects. The worst (and very rare) side effects are bone thinning (osteoporosis) and heart issues. That’s because estrogen plays a role in maintaining bone density and in healthy cholesterol. Reduction of estrogen can weaken bones and cause cardiovascular issues. Liver damage and skin reactions are also possible, but then again, less frequent. The more common side effects are not that bad and often bearable. Some common issues are hot flashes, mood changes, fatigue, nausea, joint pain, and stiffness, among others.

How Exemestane works?

Exemestane is an anti-estrogen type of medication. It is an aromatase inhibitor, working by binding to aromatase enzymes and blocking their activity. This basically inhibits the aromatization process – the process in which the enzymes bind to androgens (like testosterone) and convert them into estrogens. Most estrogen in the body is made via aromatization. Therefore, this way Aromasin significantly reduces overall estrogen levels in the body. That’s very helpful among bodybuilders who use aromatizing anabolic steroids that convert into estrogen, causing high estrogen-related side effects like gynecomastia, water retention, fat gains, and others. It allows users to continue using those anabolic steroids for physique and performance enhancement purposes, while lowering the estrogen levels and controlling those side effects. That’s why it also helps treat or prevent the estrogen receptor-positive (ER+) breast cancer. The type of cancer that grows in response to estrogen. Lowering estrogen starves cancer cells.

What are the long term side effects of Exemestane​?

Exemestane (Aromasin) is well tolerated by most users, especially bodybuilders who use anabolic steroids, because they only need to use it for short periods and in lower doses than women who need it to treat breast cancer. First off, women need more estrogen than men do. Second, they need higher doses and need to use it for longer periods for treating breast cancer than men using it for controlling high estrogen side effects from steroids. Men usually use it to lower estrogen to keep it within a normal range. With all of this mentioned, it is highly unlikely to experience long-term side effects. Still, some of the common long-term side effects are joint and muscle pain as well as bone density loss (osteopenia or osteoporosis). That’s because estrogen is necessary for muscles, joints, and bones. Cardiovascular issues, mood changes, mental health, and fatigue are also long-term possible issues.

What happens when you stop taking Exemestane?

When you stop taking Exemestane, the estrogen levels will start increasing. The effects on the body and the potential outcomes depend on the context in which you stop its use, the dosage you were taking, for how long, and so on. You may start experiencing a decrease in side effects and negative issues, assuming that you were keeping estrogen levels too low with its use, and this caused those issues. On the other hand, you may start experiencing an increase in side effects and negative effects if your estrogen levels are normally high, but you keep them in the normal range while using Aromasin. So, if your levels were too low and you experienced hot flashes, joint pain, and fatigue, they could disappear if you stop it. But if you had water retention, mood issues, and others due to high estrogen levels, they could come back if you stop it.

What is Exemestane used for​?

Exemestane is an aromatase inhibitor (AI) that the FDA approved for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It can be adjuvant treatment, switching treatment, or advanced treatment for ER+ cancer types. Sometimes it is used as a preventative measure in women at high risk of breast cancer. But it is also used off-label in bodybuilding among anabolic steroid users to control high estrogen symptoms. Anabolic steroids are converted into estrogen in the body via aromatase enzymes. Those enzymes work by converting androgens (like testosterone) into estrogens. When using steroids, you may experience high estrogen levels and all the associated symptoms. Since Aromasin lowers estrogen, it helps control all those issues, allowing users to continue their anabolic steroid use for physique and performance enhancement purposes without the side effects. Sometimes it is also used for PCT to control estrogen and boost natural testosterone production. 

Is Exemestane a steroid?

No, Exemestane (Aromasin) is not a steroid. It is not an anabolic androgenic steroid (AAS) that is commonly used for muscle building. It is actually a steroidal aromatase inhibitor (AI), which means that it is chemically related to steroids. Exemestane works as a steroid when it comes to binding to aromatase enzymes. However, instead of converting into estrogen, it blocks the aromatization process (the conversion of androgens) into estrogen. This way, it effectively reduces estrogen levels in the body. That’s why it helps treat estrogen receptor-positive breast cancer in postmenopausal women, and helps control high estrogen-related side effects from the use of anabolic steroids. Moreover, Exemestane is a suicidal and steroidal aromatase inhibitor. Suicidal means that it permanently deactivates (inhibits) the aromatase enzyme as soon as it binds to it, unlike other AIs like Anastrozole or Letrozole. The body needs to create new enzymes to convert androgens into estrogens.

What are the side effects of Exemestane 25 mg?

Exemestane 25 mg is a commonly prescribed dose for treating hormone receptor-positive breast cancer in postmenopausal women. While men using anabolic steroids also sometimes use a dosage of 25 mg of Aromasin, it is usually too high for most men. Bodybuilders aim to control their estrogen levels while using anabolic steroids, not to lower them too much. But taking 25 mg a day of Exemestane is likely to crash estrogen levels, unless you’re highly sensitive to estrogen and you use very high doses of aromatizing steroids. So, if you take 25 mg of this compound, without actually needing it (and it lowers estrogen too much), you can expect the following side effects: hot flashes, muscle and/or joint pain (arthralgia), fatigue, nausea, headaches, mood changes like depression, anxiety, or irritability, sweating (which can lead to insomnia) and others. Less common issues are osteoporosis, liver issues, cardiovascular issues, and others.

How long does Exemstane stay in your system?

Exemestane stays in your system for about 5 to 7 days. So, within one week, most of this compound will clear from your system. That’s because it has a half-life of about 24 to 27 hours. This means that it takes about this time for half of the drug’s concentration to be reduced in your body. Yet, it takes about 5 to 6 half-lives for the drug to be mostly eliminated from the system. Different factors influence clearance such as metabolism (how quickly your liver processes it), kidney function (how fast your kidneys clear it), age, weight, and overall health, activity level and diet, dosage and duration of use and others (the longer you take it for, and the higher the dosage, the longer it take to clear from the system after you stop). Nonetheless, its estrogen-suppressing effects may last even longer.

Is Exemestane a chemotherapy drug?

No, Exemestane is not a chemotherapy drug. Chemo drugs are cytotoxic, which means that they target and kill rapidly dividing cells, both cancerous and healthy cells. That’s why chemotherapy drugs are very dangerous, causing lots of side effects, and are only used in the treatment of cancer (any cancer form). Exemestane, on the other hand, is an aromatase inhibitor that blocks aromatization, lowering total estrogen levels in the body. That’s why it is only helpful at treating estrogen receptor-positive breast cancer – the type of cancer that grows as a response to estrogen. But since it lowers estrogen, bodybuilders also find it helpful for their physique and performance enhancement goals, to control the high estrogen-related side effects from the use of aromatizing anabolic steroids that convert into estrogen in the body. So, Aromasin is an aromatase inhibitor that lowers estrogen, not a chemotherapy drug (chemo) that kills rapidly dividing cells.

What to avoid when taking Exemestane?

Avoid anything that increases estrogen levels because using Exemestane, you’re trying to lower estrogen, so it directly counteracts your goals. Also, it may avoid alcohol use because it increases liver strain and may support estrogen conversion. May also avoid medications like St. John’s Wort, Rifampin, Phenytoin, and others that increase liver activity, reducing Exemestane’s effectiveness by speeding up its breakdown. Also, if you’re a woman, avoid getting pregnant while taking it. Otherwise, there are not many contraindications.

Why is Exemestane so expensive?

Exemestane is so expensive because it is more expensive to produce than other types of aromatase inhibitors like Anastrozole or Letrozole. This is the main reason. But also, its brand Aromasin by Pfizer may be more expensive than the generic Exemestane. You can use HGH.to to get the best quality Exemestane for sale on the market, making sure you will save money, as we’re working only with the best manufacturers, and we ensure the best prices for each compound that you can find on our site. Moreover, you will enjoy fast delivery, complete anonymity (as we do not ask for a prescription, so you can buy it over the counter), and convenient payment methods, among other benefits. So, Aromasin can be a pretty expensive compound, but with HGH.to you can save money while ensuring the best quality compound on the market.

Do side effects of Exemestane go away?

Yes, most side effects of Exemestane do go away after you stop using it. Additionally, the side effects may go away even while using it, as the body adjusts to its effects. Whether they go away or not depends on their nature. For example, if those side effects are associated with estrogen levels being suppressed for too long and/or too much, they will not disappear until you increase the estrogen levels. By reducing Aromasin dosage or stopping its use altogether. But if you experience side effects associated with high estrogen levels, then taking Aromasin will help control them. Moreover, there are side effects that may improve while using it. The body is getting used to the effects. Such as fatigue, mood swings, hot flashes, and others. Yet, these side effects may occur due to low estrogen, too, so it may be hard to determine what exactly causes them.

Where to buy Exemestane?

Buy Exemestane for sale at HGH.to, and you will make sure to get the highest quality compound for the lowest prices on the market. We’re the best online anabolic steroid store, including their ancillaries like Aromasin, Arimidex, Clomid, Nolvadex, and others. We’re working with the best manufacturers on the market, and that’s how we can promise the best quality. Also, we strive to offer the best prices for each compound. There are numerous other benefits to enjoy at HGH.to, such as fast delivery, a very wide variety of compounds, secure and convenient payment methods, complete anonymity as you buy prescription-only drugs over the counter (without a prescription), and numerous other advantages.