How Does Clomid Work?
Clomid that is containing Clomiphene Citrate as the main ingredient (and can be found sold as many other brand names) is a Selective Estrogen Receptor Modulator (SERM) and as all other SERMs, it works by selectively binding to estrogen receptors. However, there are many other things that you should know about this compound.
For example, Clomid, in medical settings, is actually a compound meant for women and meant for treating infertility. There are studies proving that Clomiphene Citrate is increasing the pregnancy rate and is effective in treating infertility because it is an ovulation inducting product.
The compound is binding to estrogen receptors in the body and it works as agonist in some parts of the body and antagonist in others. That’s why it increases the estrogen activity in ovaries, but is decreasing it in breast tissues.
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That’s a short explanation of how does Clomid works for fertility issues.
- Nonetheless, you might be more interested in “How Does Clomid Work For PCT?” and to answer this question, you would need to understand different things first.
Clomid and PCT
Bodybuilders and anyone who is using androgenic and anabolic steroids (AAS), would get the natural production of testosterone suppressed. That’s because when anabolic steroids are used, the body “thinks” too many hormones are produced and it shuts the natural production down.
Yet it was discovered that the mechanism of increasing LH (Luteinizing Hormone) could have a big advantage of increasing total testosterone levels.
In short, increasing LH, you would increase testosterone. And that’s why PCT is so popular and so important – it doesn’t boost testosterone, it boosts LH and therefore it helps the body maintain normal testosterone levels after you stop the administration of steroids.
Now, Clomid (Clomiphene Citrate) as mentioned is binding to estrogen receptors and that’s effective for down regulating those estrogen receptors in breast tissues during the administration of “wet” steroids such as Testosterone, Dianabol and others.
- Therefore is sometimes used as a treatment or prevention of gynecomastia, but taken in consideration that is a pretty weak anti gyno product – is rarely used for this purpose.
Instead, it can do a great job in boosting your LH (Luteinizing Hormone) and therefore your testosterone levels.
How Does Clomid Work Exactly for PCT?
As mentioned, when steroids are administered, your body stops producing testosterone. It stops producing it because your HPTA is suppressed. LH and FSH are inhibited and that’s why your body doesn’t produce Testosterone anymore.
Since most Testosterones are produced in testicles, if you have a too long administration of “external source of Testosterone” the male balls are shrinking (there’s no need for them to produce more Test).
Post Cycle Therapy (PCT) plan is helping your body to recover back normal HPTA after an androgenic and anabolic steroid (AAS) cycle.
Clomid (Clomiphene Citrate) doesn’t mimic LH as HCG (Human Chorionic Gonadotropin) does. When HCG mimics LH – your test levels increase and this still suppresses LH and FSH naturally. Clomid, doesn’t mimic it, so that’s why Clomid is a good PCT medicine whilst HCG is not.
Instead, Clomid is stimulating the hypophysis and that’s leading to an increased release of gonadotropins. These are some protein hormones that are being secreted by the gonadotrope cells of the pituitary gland. They are stimulating a higher and faster release of the FSH and LH.
- In short, Clomid stimulates hypophysis.
- This results in more gonadotropins.
- This results in more FSH and LH.
- This results in more testosterone levels.
Until your body recovers, you artificially maintain testosterone levels high without getting natural production suppressed.
In other words, the pituitary gland is controlling the amount of testosterone that is made in your testicles. The gland “decides” whether you need more or less testosterone depending on your estrogen levels (since testosterone is converted into estrogen). If you get too much testosterone – too much conversion of estrogen occurs and your gland signals to stop releasing gonadotropins, LH and FSH.
The introduction of Clomid (Clomiphene Citrate) is blocking the estrogen at the pituitary gland as it works, selectively, on your estrogen receptors.
As a result, the pituitary gland doesn’t “see” so much estrogen and it makes more LH. More LH, as mentioned, results in more testosterone.
When you use testosterone directly, that’s making your pituitary gland receive signals that too much estrogen is there and makes your testicles stop producing testosterone.
That’s how Clomid works, and that’s why Clomid is such a popular Post Cycle Therapy (PCT) medicine.
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