Tamoxifen Adverse Effects
Tamoxifen Citrate, mostly known as brand Nolvadex including others, is a popular medication both in medical settings as well as for bodybuilding purposes. Tamoxifen is a Selective Estrogen Receptor Modulator (SERM). Because of how it works – the compound is very effective for various purposes.
In medical settings, Tamoxifen is seen as a compound that can prevent or treat breast cancer in women. But is also a compound used for treating gynecomastia in men. There are various other uses too.
In the bodybuilding world, Tamoxifen is a compound that is used during the cycle of anabolic steroids to prevent gynecomastia or treat it. But is also used after the cycle of anabolic steroids ends as a PCT medication.
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As much as you can see, Tamoxifen Citrate (Nolvadex) can be used by a lot of different people for many different needs. Is quite obvious that Tamoxifen adverse effects greatly depend on the reason why exactly you use it. As well as who exactly uses it. Because there are studies proving that males are way less likely to get negative side effects compared to women. That’s simply because of how our bodies react to the compound.
Therefore, whilst women are way more likely to get Tamoxifen adverse effects than men – they both should use the compound in the proper manner. Users need to use it according to their own needs to avoid negative side effects.
- NOTE! If you got Tamoxifen prescribed for a health condition and want to find out more information about it – talk to a doctor. Your doctor is going to help you best by offering info about it and about its side effects.
We’re an anabolic steroid source so you would mostly find info about Tamoxifen for bodybuilders.
Tamoxifen Side Effects Explaining
Men are getting similar side effects from Tamoxifen when they run it for PCT. Or for gynecomastia control during the cycle of aromatized steroids.
Nonetheless, side effects may be different. It depends on the administered dosage too.
In the end, there are some people who report reduced libido. But there are also others suggesting that it increases libido. That’s possibly taken into consideration that Tamoxifen increases testosterone (increases libido). But is also known to increase SHBG (decreases libido) which is problematic for bodybuilders.
Most side effects would appear when Nolvadex is not used properly (too high doses or/ and too long administration).
Tamoxifen Side Effects SHBG Related
Talking about SHBG – remember that Tamoxifen is SERM, which means that although it is an anti-estrogenic medication, it actually works as an estrogen agonist in some parts of the body. It means that it boosts the estrogen activity to those receptors. For example, it works as an estrogenic agonist in the liver. That’s how it increases Sex hormone Binding Globulin (SHBG). Thereby it lowers free testosterone in the body. That’s detrimental for bodybuilders because free testosterone is having a huge correlation with increased lean muscle mass, increased strength, libido, etc.
Due to the increase of SHBG and lowering free testosterone – Tamoxifen adverse effects are capable of hurting the bodybuilders’ gains. That’s especially due to the same activity of Tamoxifen in your liver.
The compound might suppress the production of IGF-1. This is an extremely popular and extremely important hormone for building muscle tissue.
- In fact, this is considered one of the most powerful peptide hormones. Even more powerful than Growth Hormone itself for growing lean muscle mass.
Is quite obvious that bodybuilders are searching for a way to keep IGF-1 as high as possible. But Tamoxifen is a compound that may contribute to lowering IGF-1 levels. That’s how it may be hurting your gains.
Other Tamoxifen Side Effects
One more thing to mention about Tamoxifen adverse effects – mood swings. This is one of the most common side effects of all SERMs – both Nolvadex (Tamoxifen Citrate) and Clomid (Clomiphene Citrate). Bodybuilders are often reporting they are getting pretty harsh mood swings, they can get very emotional and sometimes even depressive states.
But then again, these are some of the most reported and most known as well as worst side effects of Tamoxifen among bodybuilders which are likely to occur only in certain cases (abuse, low tolerance to it, etc.).
- There are simple Tamoxifen side effects such as vomiting, hot flashes, numbness, dizziness, diarrhea, nausea, and others but then again, when Tamoxifen is used properly – is unlikely you would get any side effects.
Keep in mind that dosages are highly individual, depending on many different factors.
But generally, most people find their sweet dose in the range of 10-80 mg per day or every other day. Most commonly – 20-40 mg daily is what people find their best.
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